Independent Career (undergraduate co-authors are underlined)

  1. Floyd, M.D.; Ryan, L.Y.; Hendsey, J.L.; Nicholson, J.M.; Palaia, A.T.; Isaacs, A.K. "Copper-catalyzed three-component synthesis of pyyrole-substituted 1,2-dihydroisoquinolines" Synth. Commun. 2022
  2. Basu, A.C.; Hill, A.S.; Isaacs, A.K.; Mondoux, M.A.; Mruczek, R.E.; Narita, T. “Integrative STEM education for Undergraduate Neuroscience: Design and Implementation” Neuroscience Letters, 2021, 746.
  3. Bosse, A.; Tsougranis, G.; DeTroia, C.; Tejidor, F.; Isaacs, A.K. “Cu(I)-Catalyzed Synthesis of β,γ-unsaturated Amides”  Synlett. 2018, 29, 463.
  4. Basu, A.C.; Mondoux, M.A.; Whit, J.L.; Isaacs, A.K.; Narita, T. “Flipping the Classroom to Address STEM Concepts in an Introductory  Neuroscience Course: Gains in Interdisciplinary Awareness” J. Undergrad. Neurosci. Educ. 2017, 16, A110
  5. ​Chen, J.; Namirembe, S.; Lauchert, L.; Tsougranis, G.; Isaacs, A.K. “Cu(I)-Catalyzed Synthesis of N-Tosyl-4-Iminoquinolizines” Tet. Lett. 2015, 56, 4105.  

Post-doctoral and Graduate Career

  1. Isaacs, A.K.; Qi, S.; Sarpong, R.; Casida, J.E.; “Insect Ryanodine Receptor: Distinct but Couple Insecticide Binding Sites for [N-C3H3]Chlorantraniliprole, Flubendiamide, and [3H]Ryanodine” Chem. Res. Toxicol. 2012, 25, 1571-1573.
  2. Winkler, J.D.; Isaacs, A.K.; Xiang, C.; Baubet, V.; Dahmane, N.; “Design, synthesis, and biological evaluation of estrone-derived hedgehog signaling inhibitors” Tetrahedron 2011, 67, 10261.
  3. Isaacs, A.K.; Xiang, C.; Baubet, V.; Dahmane, N.; Winkler, J.D.; “Studies Directed toward the Elucidation of the Pharmacophore of Steroid-Based Sonic Hedgehog Signaling Inhibitors” Org. Lett. 2011, 13, 5140.
  4. Yano, T.; Kassovska-Bratinova, S.; The, J.S.; Winkler, J.; Sullivan, K.; Isaacs, A.K.; Schechter, N.M; Rubin, H.; “Reduction of clofazimine by mycobacterial type 2 NADH:quinone oxidoreductase: a pathway for the generation of bactericidal levels of reactive oxygen species. J. Biol. Chem. 2011, 286, 10276.
  5. Winkler, J.D.; Isaacs, A.K.; Holderbaum, L.; Tatard, V.; Dahmane, N., “Design and Synthesis of Inhibitors of Hedgehog Signaling based on the Alkaloid Cyclopamine” Org. Lett. 2009, 11, 2824-2827.
  6. Choi, S.; Isaacs, A.K.; Winkler, J.D.; DeGrado, W.F.; et al., “De novo design and in vivo activity of conformationally restrained antimicrobial arylamide foldamers” PNAS 2009, 106, 6968-6973.

Undergraduate Career

  1. Quinn, K.J.; Isaacs, A.K.; DeChristopher, B.A.; Szklarz, S.C.; Arvary, R.A., “Asymmetric Total Synthesis of Rollicosin” Org. Lett. 2005, 7, 1243-1245.
  2. Quinn, K.J.; Isaacs, A.K.; Arvary, R.A., “Concise Total Synthesis of (-)-Muricatacin by Tandem Ring-Closing/Cross Metathesis.” Org. Lett. 2004, 6, 4143-4145.

Patents

  1. Dahmane, N., Winkler, J., Isaacs, A.K. “Compounds and Methods for the Prevention and Treatment of Cancer” U.S. Patent  8,759,367, issued June 24, 2014.